GPCRdb

CHEMBL484598

Agent/drug
Bioactivity

CHEMBL484598

SMILES	CCCN1CCO[C@@H]2c3cc4c(cc3CC[C@H]21)CNC4=O
InChIKey	FTCVLHZRRJVLPD-HZPDHXFCSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	2
Molecular weight (Da)	286.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pKi	6.08	6.08	6.08	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.38	8.38	8.38	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	6.57	6.57	6.57	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	8.85	8.85	8.85	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL484598

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.