GPCRdb

CHEMBL484599

Agent/drug
Bioactivity

CHEMBL484599

SMILES	CCCN1CCO[C@@H]2c3cc(C(N)=O)ccc3CC[C@H]21
InChIKey	XKTRZPQOQOCNJU-HUUCEWRRSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	3
Molecular weight (Da)	274.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pKi	5.92	5.92	5.92	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	7.83	7.83	7.83	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Rat	Dopamine	A	pIC50	6.39	6.39	6.39	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pEC50	7.30	7.30	7.30	ChEMBL
D₃	DRD3	Rat	Dopamine	A	pIC50	8.38	8.38	8.38	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	8.64	8.64	8.64	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL484599

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.