CHEMBL4650998


SMILES Cc1cc(/C=C/C=C/c2ccc(N(C)C)cc2)cc(C)[n+]1CCN1CCN(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)CC1
InChIKey UKIVPXWUVXIMDE-UHFFFAOYSA-O

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 14
Molecular weight (Da) 780.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.41 6.41 6.41 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.02 8.02 8.02 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.83 6.83 6.83 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.52 8.52 8.52 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 8.63 8.74 8.85 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.86 8.08 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database