CHEMBL1181680


SMILES CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)C(=O)/C=C/c1ccccc1
InChIKey XIMFQVXENHJKEO-OQKWZONESA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 13
Molecular weight (Da) 517.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 7.6 7.6 7.6 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.7 6.7 6.7 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.9 5.9 5.9 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.9 5.9 5.9 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.0 6.0 6.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.1 6.1 6.1 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.1 6.1 6.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database