GPCRdb

CHEMBL4872932

Agent/drug
Bioactivity

CHEMBL4872932

SMILES	CC(C)[C@@H]1CNC(=N)N1C[C@@H]1CCCN1[C@@H](Cc1ccccc1)N1C[C@@H]([C@@H](C)O)N(CC2CCC(C(C)(C)C)CC2)C1=N
InChIKey	SMMDVRPOQHVKBQ-MFNYXIFISA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	4
Rotatable bonds	10
Molecular weight (Da)	593.5

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₄	MC4R	Mouse	Melanocortin	A	pKd	6.50	6.50	6.50	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₁	MSHR	Mouse	Melanocortin	A	pEC50	6.22	6.22	6.22	ChEMBL
MC₅	MC5R	Mouse	Melanocortin	A	pEC50	6.31	6.31	6.31	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL4872932

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.