CHEMBL4743324


SMILES Cn1ccc2ccc(OCCCN3CCC(c4noc5cc(F)ccc45)CC3)cc2c1=O
InChIKey XJPFLUQFOAAHFE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.89 6.89 6.89 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 6.93 6.93 6.93 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.04 8.04 8.04 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.92 7.92 7.92 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database