CHEMBL491930
| SMILES | O=C1OC2(CCN(C(=O)Nc3cnc(-c4ccccc4)cn3)CC2)c2ccccc21 |
| InChIKey | MKVJQAZEXGSAIT-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 2 |
| Molecular weight (Da) | 400.2 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| Y5 | NPY5R | Human | Neuropeptide Y | A | pKi | 8.62 | 8.62 | 8.62 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| Y5 | NPY5R | Rat | Neuropeptide Y | A | pIC50 | 8.77 | 8.77 | 8.77 | ChEMBL |
| Y5 | NPY5R | Mouse | Neuropeptide Y | A | pIC50 | 8.77 | 8.77 | 8.77 | ChEMBL |
| Y5 | NPY5R | Human | Neuropeptide Y | A | pIC50 | 8.21 | 8.41 | 8.62 | ChEMBL |