CHEMBL49231


SMILES COc1ccccc1N1CCN(CNC(=O)c2ccc(Cl)cc2)CC1
InChIKey PNUAYJRARXKVQH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 359.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.85 8.05 8.46 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.57 6.57 6.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.46 6.52 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.08 8.08 8.08 ChEMBL