GPCRdb

CHEMBL4878215

Agent/drug
Bioactivity

CHEMBL4878215

SMILES	N/C(=N\C(=O)NCc1ccccc1)NC1CCc2nc(N)sc2C1
InChIKey	KOIIIBWVKNCMBP-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	4
Rotatable bonds	3
Molecular weight (Da)	344.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pKi	6.26	6.26	6.26	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	5.30	5.30	5.30	ChEMBL
H₁	HRH1	Human	Histamine	A	pKi	5.92	5.92	5.92	ChEMBL
H₂	HRH2	Human	Histamine	A	pKi	6.29	6.29	6.29	ChEMBL
H₃	HRH3	Human	Histamine	A	pKi	5.48	5.48	5.48	ChEMBL
H₄	HRH4	Human	Histamine	A	pKi	4.52	4.52	4.52	ChEMBL

Showing 1 to 6 of 6 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₂	HRH2	Human	Histamine	A	pEC50	5.36	6.02	6.67	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL4878215

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.