CHEMBL492677


SMILES CN1CCN(c2cc(NCc3ccccc3)nc(N)n2)CC1
InChIKey GXRZHULPUGZJMQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 298.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 7.01 7.36 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Rat Histamine A pEC50 6.31 6.31 6.31 ChEMBL
H4 HRH4 Human Histamine A pEC50 7.19 7.49 7.9 ChEMBL