CHEMBL493486


SMILES COc1ccccc1OCCNC[C@@H]1COCC(c2ccccc2)(c2ccccc2)O1
InChIKey HIASEHRDTBGCHW-HSZRJFAPSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 419.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.25 7.46 7.66 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.56 7.67 7.78 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.86 8.9 8.94 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.18 9.21 9.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database