GPCRdb

CANADINE

Agent/drug
Bioactivity

CANADINE

SMILES	COc1ccc2c(c1OC)CN1CCc3cc4c(cc3[C@@H]1C2)OCO4
InChIKey	VZTUIEROBZXUFA-INIZCTEOSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	0
Rotatable bonds	2
Molecular weight (Da)	339.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₁	DRD1	Human	Dopamine	A	pKi	7.18	7.24	7.31	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	6.92	7.01	7.10	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	6.36	6.36	6.36	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	6.31	6.31	6.31	ChEMBL
D₅	DRD5	Human	Dopamine	A	pKi	7.21	7.21	7.21	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1A	ADA1A	Human	Adrenoceptors	A	pIC50	5.27	5.27	5.27	ChEMBL

Showing 1 to 1 of 1 entry

CANADINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.