(R,S)-IFENPRODIL


SMILES C[C@@H]([C@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1
InChIKey UYNVMODNBIQBMV-KKSFZXQISA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 325.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 6.85 6.85 6.85 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.29 6.29 6.29 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.8 5.8 5.8 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.02 7.02 7.02 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.13 6.13 6.13 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.9 5.0 5.1 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.9 5.05 5.2 ChEMBL