CHEMBL502347


SMILES Nc1nc2c(c(N3CC[C@@H](N)C3)n1)CCCc1ccccc1-2
InChIKey SDTRYHWIXVHTLM-GFCCVEGCSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 295.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Rat Histamine A pKi 8.42 8.42 8.42 ChEMBL
H4 HRH4 Human Histamine A pKi 8.3 8.32 8.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pEC50 8.24 8.24 8.24 ChEMBL
H4 HRH4 Rat Histamine A pEC50 8.0 8.0 8.0 ChEMBL