GPCRdb

CHEMBL1278088

Agent/drug
Bioactivity

CHEMBL1278088

SMILES	Nn1c(CCCCN2CCN(c3ccc4ccccc4n3)CC2)nc2c(c1=O)CCCC2
InChIKey	WFQOETMVYMINSA-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	7
Hydrogen bond donors	1
Rotatable bonds	6
Molecular weight (Da)	432.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	9.15	9.15	9.15	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pEC50	7.65	7.65	7.65	ChEMBL
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pIC50	8.85	8.85	8.85	ChEMBL
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pIC50	6.00	6.00	6.00	ChEMBL
H₁	HRH1	Human	Histamine	A	pIC50	6.00	6.00	6.00	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL1278088

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.