CHEMBL503605


SMILES O=C(c1cc2cc(Cl)ccc2[nH]1)N1CCNCC1
InChIKey RNGVSSIIHLHHSN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 263.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Rat Histamine A pKi 8.4 8.4 8.4 ChEMBL
H4 HRH4 Human Histamine A pKi 7.59 7.75 7.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pEC50 7.75 7.75 7.75 ChEMBL
H4 HRH4 Rat Histamine A pEC50 7.51 7.51 7.51 ChEMBL