GPCRdb

CHEMBL499324

Agent/drug
Bioactivity

CHEMBL499324

SMILES	CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccc(F)cc4C#N)no3)ccc21
InChIKey	NVSKXWGRIBCWNF-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	1
Rotatable bonds	6
Molecular weight (Da)	453.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₂	CNR2	Human	Cannabinoid	A	pKi	8.16	8.16	8.16	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Human	Cannabinoid	A	pEC50	6.15	6.15	6.15	ChEMBL
CB₂	CNR2	Rat	Cannabinoid	A	pEC50	9.89	9.89	9.89	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pEC50	9.07	9.28	9.48	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL499324

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.