CHEMBL509540


SMILES Nc1nc2c(c(N3CCNCC3)n1)CCCc1ccccc1-2
InChIKey KUZRWWLVBUPCRK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 295.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Rat Histamine A pKi 8.12 8.12 8.12 ChEMBL
H4 HRH4 Human Histamine A pKi 7.1 7.13 7.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pEC50 7.74 7.74 7.74 ChEMBL
H4 HRH4 Rat Histamine A pEC50 7.83 7.83 7.83 ChEMBL