CHEMBL517108


SMILES CNC(=O)[C@H](Cc1ccc2ccccc2c1)N1CCN(C(=O)[C@H](N)Cc2ccc(F)cc2)[C@@H](C)C1=O
InChIKey GQPNXZXCXCXNAT-MUEKUWCCSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 490.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 4.63 4.63 4.63 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.55 5.55 5.55 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.01 7.01 7.01 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 5.64 5.64 5.64 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 6.52 6.52 6.52 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 7.43 7.43 7.43 ChEMBL