GPCRdb

CHEMBL128699

Agent/drug
Bioactivity

CHEMBL128699

SMILES	Cc1cc(C)c(N2CCN(C(=O)COc3ccc4cccc(N5CCN(C)CC5)c4c3)CC2)c(C)c1
InChIKey	CPPNLMBHDVESPV-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	0
Rotatable bonds	5
Molecular weight (Da)	486.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	6.93	6.93	6.93	ChEMBL
5-HT_1B	5HT1B	Human	5-Hydroxytryptamine	A	pKi	8.85	8.85	8.85	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	8.72	8.72	8.72	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1B	5HT1B	Human	5-Hydroxytryptamine	A	pEC50	7.60	7.60	7.60	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL128699

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.