GPCRdb

GW9508

Agent/drug
Bioactivity

GW9508

SMILES	O=C(O)CCc1ccc(NCc2cccc(Oc3ccccc3)c2)cc1
InChIKey	DGENZVKCTGIDRZ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	2
Rotatable bonds	8
Molecular weight (Da)	347.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Structure pdb	8H4K

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₃	PE2R3	Human	Prostanoid	A	pKi	6.40	6.40	6.40	ChEMBL
FFA1	FFAR1	Human	Free fatty acid	A	pKi	6.66	6.66	6.66	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

FFA1	FFAR1	Human	Free fatty acid	A	pEC50	7.30	7.30	7.30	Guide to Pharmacology
FFA1	FFAR1	Rat	Free fatty acid	A	pEC50	7.00	7.00	7.00	ChEMBL
FFA1	FFAR1	Human	Free fatty acid	A	pEC50	4.75	6.89	7.89	ChEMBL
FFA4	FFAR4	Human	Free fatty acid	A	pEC50	5.46	5.46	5.46	Guide to Pharmacology
FFA4	FFAR4	Human	Free fatty acid	A	pEC50	5.46	5.57	5.85	ChEMBL

Showing 1 to 5 of 5 entries

GW9508

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Structure pdb	8H4K

Compound is not listed as a drug.