GPCRdb

CHEMBL5177001

Agent/drug
Bioactivity

CHEMBL5177001

SMILES	CCC(=O)N(c1ccccc1)C1CCN(C(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)C/C=C(\F)[C@@H](N)Cc2ccc(O)cc2)CC1
InChIKey	UJVAKTSNKRZVJI-XRELOVPQSA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	4
Rotatable bonds	14
Molecular weight (Da)	657.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	6.43	6.43	6.43	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	6.43	6.43	6.43	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Mouse	Opioid	A	pIC50	6.87	6.87	6.87	ChEMBL
δ	OPRD	Human	Opioid	A	pEC50	5.41	5.41	5.41	ChEMBL
μ	OPRM	Mouse	Opioid	A	pIC50	6.74	6.74	6.74	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL5177001

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.