CHEMBL4803454


SMILES N[C@@]1(C(=O)O)[C@H](CSc2ccccc2)[C@H](O)[C@@H]2[C@H]1[C@H]2C(=O)O
InChIKey XMENKXPGVGTNAZ-VWMNBNTDSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 323.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.58 7.58 7.58 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.51 7.51 7.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 6.26 6.26 6.26 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 6.47 6.47 6.47 ChEMBL