CHEMBL4803695


SMILES CN(C)c1ccc2c(-c3ccc(C(=O)NCCNC(=O)CCc4cn(CCCCC5CCN(CC(=O)N6c7ccccc7NC(=O)c7ccccc76)CC5)cn4)cc3C(=O)[O-])c3ccc(=[N+](C)C)cc-3oc2c1
InChIKey RTVAKAAPGHVGBW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 11
Hydrogen bond donors 3
Rotatable bonds 17
Molecular weight (Da) 983.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.56 6.56 6.56 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.43 8.43 8.43 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.89 6.89 6.89 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 8.36 8.49 8.62 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.21 8.48 8.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database