CHEMBL4846866


SMILES CN1CCN(Cc2ccc(OCCCCN3CCC(c4noc5cc(F)ccc45)CC3)cc2)CC1
InChIKey NZDANPPRKVYGPL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 480.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 6.19 6.19 6.19 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.45 6.45 6.45 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
H3 HRH3 Human Histamine A pKi 8.04 8.04 8.04 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.37 6.37 6.37 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.42 7.42 7.42 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.37 8.37 8.37 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.91 7.91 7.91 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.72 8.72 8.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database