CHEMBL484778


SMILES CC(C)c1nccc2c1c(Sc1ccc(Cl)c(Cl)c1)c1n2CC[C@H]1CC(=O)O
InChIKey LUZBJNWFEDHIPR-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 434.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FP PF2R Human Prostanoid A pKi 4.59 4.59 4.59 ChEMBL
DP1 PD2R Human Prostanoid A pKi 9.19 9.19 9.19 ChEMBL
EP1 PE2R1 Human Prostanoid A pKi 4.54 4.54 4.54 ChEMBL
EP2 PE2R2 Human Prostanoid A pKi 5.13 5.13 5.13 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 6.15 6.15 6.15 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 5.18 5.18 5.18 ChEMBL
DP2 PD2R2 Human Prostanoid A pKi 6.63 6.63 6.63 ChEMBL
TP TA2R Human Prostanoid A pKi 5.3 5.3 5.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Human Prostanoid A pIC50 8.3 8.98 9.66 ChEMBL