CHEMBL4850448


SMILES Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(c1ccccc1)C(F)(F)F
InChIKey YJTHKEYGLMPNKT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 6
Molecular weight (Da) 414.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 4.76 4.76 4.76 ChEMBL
H2 HRH2 Human Histamine A pKi 6.64 6.64 6.64 ChEMBL
H1 HRH1 Human Histamine A pKi 4.27 4.27 4.27 ChEMBL
H3 HRH3 Human Histamine A pKi 4.5 4.5 4.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database