CHEMBL4851044


SMILES CN1CCC(=C(F)c2cccc(NC(=O)c3c(F)cc(F)cc3F)n2)CC1
InChIKey QCXSPEMRGSBSEO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 379.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pIC50 7.71 8.6 9.49 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 5.67 5.67 5.67 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 5.07 5.07 5.07 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 5.15 5.15 5.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 5.31 5.31 5.31 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 6.82 6.82 6.82 ChEMBL