CHEMBL4863523


SMILES Cc1nc(N)sc1CCCN/C(N)=N/C(=O)NC(C)c1ccc(OC(F)(F)F)cc1
InChIKey JHCLKMYQQVHYLG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 7
Molecular weight (Da) 444.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 5.09 5.09 5.09 ChEMBL
H2 HRH2 Human Histamine A pKi 6.9 6.9 6.9 ChEMBL
H1 HRH1 Human Histamine A pKi 4.66 4.66 4.66 ChEMBL
H3 HRH3 Human Histamine A pKi 4.84 4.84 4.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database