CHEMBL523048


SMILES c1ccc(-c2ccccc2OC(C2=NCCN2)c2ccccc2)cc1
InChIKey XXOSLSPHUHLICG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 328.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.02 6.02 6.02 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.69 6.69 6.69 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.62 6.62 6.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 6.11 6.11 6.11 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 6.0 6.0 6.0 ChEMBL