GPCRdb

histamine

histamine

SMILES	NCCc1cnc[nH]1
InChIKey	NTYJJOPFIAHURM-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	2
Molecular weight (Da)	111.1

Database connections

Guide To Pharmacology DrugBank Drug Central ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7DFL 8JXT 8POK 8YUU 7YFC 8HN8
Ligand site mutations	H₁ H₃ H₄

Bioactivities

Affinity
Potency

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

histamine

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Endogenous
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 3

Phase III 9

Approved Yes

Database connections

Guide To Pharmacology DrugBank Drug Central ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7DFL 8JXT 8POK 8YUU 7YFC 8HN8
Ligand site mutations	H₁ H₃ H₄

Sankey plot

Drug Information

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

This ligand is endogenous.