CHEMBL532818


SMILES COc1cccc2c(NCCNc3ccnc4c(OC)cccc34)ccnc12
InChIKey OBEXOFONJDJASX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 374.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.49 6.49 6.49 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.71 6.71 6.71 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 5.7 5.7 5.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.51 5.51 5.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database