GPCRdb

CHEMBL5222201

Agent/drug
Bioactivity

CHEMBL5222201

SMILES	O=C1CCc2ccccc2N1CCCN1CCN(c2ccccn2)CC1
InChIKey	UWUBDOPGNONVDN-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	5
Molecular weight (Da)	350.2

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pKi	5.56	5.56	5.56	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	5.59	5.59	5.59	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	8.65	8.65	8.65	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₄	DRD4	Human	Dopamine	A	pIC50	7.17	7.17	7.17	ChEMBL
D₄	DRD4	Human	Dopamine	A	pEC50	7.91	7.99	8.07	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL5222201

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.