CHEMBL490634


SMILES COc1c(OCCF)cccc1C(=O)C1CCN(CCc2ccc([N+](=O)[O-])cc2)CC1
InChIKey VSDLSICGFMFZRC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 430.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.74 5.74 5.74 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.21 5.21 5.21 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.98 5.98 5.98 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.76 5.76 5.76 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database