GPCRdb

CHEMBL5399270

Agent/drug
Bioactivity

CHEMBL5399270

SMILES	Clc1cccc(N2CCN(CCC3(c4ccccn4)CCOCC3)CC2)c1Cl
InChIKey	CNKXCQYEDYCLBH-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	5
Molecular weight (Da)	419.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

μ	OPRM	Human	Opioid	A	pKi	6.16	6.16	6.16	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	6.92	6.92	6.92	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	7.33	7.33	7.33	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

μ	OPRM	Mouse	Opioid	A	pEC50	5.19	5.69	6.07	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	6.57	6.86	7.01	ChEMBL
D₃	DRD3	Human	Dopamine	A	pIC50	6.57	6.57	6.57	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL5399270

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.