CHEMBL5028619


SMILES CC(=O)N[C@H](CCCN)C(=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NCCN1CCN(CCC(=O)NC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc43)CC2)CC1
InChIKey ZFXGEVATMHZGBZ-BHQPUTRGSA-N

Chemical properties

Hydrogen bond acceptors 13
Hydrogen bond donors 10
Rotatable bonds 22
Molecular weight (Da) 916.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.31 5.31 5.31 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.07 5.07 5.07 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.08 9.08 9.08 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.27 7.27 7.27 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.4 7.4 7.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database