GPCRdb

CHEMBL5403268

Agent/drug
Bioactivity

CHEMBL5403268

SMILES	COCCC(=O)N[C@H]1CC[C@H](CCN2CCN(c3cccc(OC)c3F)CC2)CC1
InChIKey	SVPFZRJDQVOOKQ-WGSAOQKQSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	9
Molecular weight (Da)	421.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	7.16	7.16	7.16	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	7.53	7.53	7.53	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	6.32	6.32	6.32	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.88	8.88	8.88	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	6.13	6.13	6.13	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	7.96	8.54	9.13	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	8.54	8.54	8.54	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL5403268

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.