GPCRdb

CHEMBL5407403

Agent/drug
Bioactivity

CHEMBL5407403

SMILES	CC(C)[C@H]1CC[C@@H](N2CCC(n3c(CNC(=O)c4cccnc4)cc4ccccc43)CC2)CC1
InChIKey	QTTZYJWQRRKUIV-WZJNIGMMSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	6
Molecular weight (Da)	458.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	7.18	7.18	7.18	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	6.95	6.95	6.95	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	8.27	8.27	8.27	ChEMBL
NOP	OPRX	Human	Opioid	A	pKi	9.12	9.12	9.12	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	6.71	6.71	6.71	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	7.11	7.11	7.11	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	7.37	7.37	7.37	ChEMBL
NOP	OPRX	Human	Opioid	A	pEC50	7.71	7.71	7.71	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL5407403

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.