GINKOLIDE B


SMILES C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@@]34[C@H]5C[C@@H](C(C)(C)C)[C@]36[C@@H](OC(=O)[C@@H]6O)O[C@@]4(C(=O)O5)[C@@]12O
InChIKey SQOJOAFXDQDRGF-MMQTXUMRSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 3
Rotatable bonds 0
Molecular weight (Da) 424.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Guinea pig Platelet-activating factor A pKi 6.06 6.06 6.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Guinea pig Platelet-activating factor A pEC50 6.75 6.75 6.75 ChEMBL
PAF PTAFR Guinea pig Platelet-activating factor A pIC50 6.13 6.3 6.38 ChEMBL
PAF PTAFR Human Platelet-activating factor A pIC50 6.89 6.89 6.89 ChEMBL