GPCRdb

CHEMBL5427695

Agent/drug
Bioactivity

CHEMBL5427695

SMILES	COc1cccc(N2CCN(CC[C@H]3CC[C@H](NC(=O)N(C)C)CC3)CC2)c1F
InChIKey	MUUSXXFKLPMJKL-IYARVYRRSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	6
Molecular weight (Da)	406.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	7.47	7.47	7.47	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	7.47	7.47	7.47	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	6.87	6.87	6.87	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.03	8.03	8.03	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	5.90	5.90	5.90	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	8.39	8.98	9.57	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	8.79	8.79	8.79	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL5427695

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.