GPCRdb

CHEMBL5438081

Agent/drug
Bioactivity

CHEMBL5438081

SMILES	COCCC(=O)N1CCC(CCCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1
InChIKey	ZWPVOADZQCQUKW-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	8
Molecular weight (Da)	441.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pKi	7.71	7.71	7.71	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	9.02	9.02	9.02	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	7.96	7.98	8.00	ChEMBL
D₃	DRD3	Human	Dopamine	A	pIC50	7.89	7.89	7.89	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	7.79	7.79	7.80	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL5438081

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.