GPCRdb

CHEMBL557937

Agent/drug
Bioactivity

CHEMBL557937

SMILES	CN1CC[C@]23Cc4c(c5ccccc5n4C)C[C@]2(Cc2ccc(O)cc23)C1
InChIKey	WDTIJGFXRJTCSB-DNQXCXABSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	0
Molecular weight (Da)	358.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	6.57	6.57	6.57	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	5.95	5.95	5.95	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	7.40	7.40	7.40	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	7.19	7.19	7.19	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	7.21	7.21	7.21	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	6.76	6.76	6.76	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL557937

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.