CHEMBL5206148


SMILES COc1ccc2[nH]cc(Cc3nnc(Cc4cccc(C(F)(F)F)c4)n3CCCc3c[nH]cn3)c2c1
InChIKey FWYGJAUWVCVBHP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 494.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST1 SSR1 Human Somatostatin A pKi 6.44 6.44 6.44 ChEMBL
SST4 SSR4 Human Somatostatin A pKi 8.74 8.74 8.74 ChEMBL
SST2 SSR2 Human Somatostatin A pKi 5.77 5.77 5.77 ChEMBL
SST3 SSR3 Human Somatostatin A pKi 5.95 5.95 5.95 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST4 SSR4 Human Somatostatin A pEC50 9.0 9.0 9.0 ChEMBL