CHEMBL607351


SMILES CN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@@]3(OCc2ccccc2)[C@H]1C5
InChIKey JIZIIPYPMGBADK-QLBRKBSLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 391.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 8.93 8.93 8.93 ChEMBL
μ OPRM Rat Opioid A pKi 9.92 9.92 9.92 ChEMBL
δ OPRD Human Opioid A pKi 8.98 8.98 8.98 ChEMBL
κ OPRK Human Opioid A pKi 8.9 8.9 8.9 ChEMBL
μ OPRM Human Opioid A pKi 9.35 9.35 9.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 8.82 8.82 8.82 ChEMBL
μ OPRM Human Opioid A pEC50 9.49 9.49 9.49 ChEMBL