GPCRdb

CHEMBL571992

Agent/drug
Bioactivity

CHEMBL571992

SMILES	CCCN(CCN1CCN(c2nccc3ccccc23)CC1)[C@H]1CCc2nc(N)sc2C1
InChIKey	SNMHDHJEXUFVCO-FQEVSTJZSA-N

Chemical Properties

Hydrogen bond acceptors	7
Hydrogen bond donors	1
Rotatable bonds	7
Molecular weight (Da)	450.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Rat	Dopamine	A	pKi	6.57	6.57	6.57	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	6.57	6.57	6.57	ChEMBL
D₃	DRD3	Rat	Dopamine	A	pKi	8.65	8.65	8.65	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.65	8.65	8.65	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	6.94	6.94	6.94	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	9.09	9.15	9.28	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL571992

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.