PALTUSOTINE


SMILES N#Cc1cccc(-c2ccc3ncc(-c4cc(F)cc(F)c4)c(N4CCC(N)CC4)c3c2)c1O
InChIKey GHILNKWBALQPDP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 456.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 7YAC

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST2 SSR2 Dog Somatostatin A pEC50 8.18 8.18 8.18 ChEMBL
SST2 SSR2 Rat Somatostatin A pEC50 8.92 8.92 8.92 ChEMBL
SST4 SSR4 Human Somatostatin A pEC50 6.0 6.0 6.0 ChEMBL
SST2 SSR2 Human Somatostatin A pEC50 9.6 9.6 9.6 ChEMBL