CHEMBL5268503


SMILES CN(C)c1ccc2c(-c3ccc(-c4cn(CCCCCn5cc(CCCCCN6CCC(COC(=O)Nc7ccc(F)cc7-c7ccc(F)c(Cl)c7)CC6)nn5)nn4)cc3C(=O)[O-])c3ccc(=[N+](C)C)cc-3oc2c1
InChIKey PXHIFOLPKHLYBX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 13
Hydrogen bond donors 1
Rotatable bonds 20
Molecular weight (Da) 1038.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.92 7.92 7.92 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.59 8.59 8.59 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.51 8.51 8.51 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.58 7.58 7.58 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.42 8.42 8.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database