GPCRdb

m-chlorophenylpiperazine

Agent/drug
Bioactivity

m-chlorophenylpiperazine

SMILES	Clc1cccc(N2CCNCC2)c1
InChIKey	VHFVKMTVMIZMIK-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	1
Rotatable bonds	1
Molecular weight (Da)	196.1

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	5.62	6.78	7.64	ChEMBL
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKd	7.00	7.00	7.00	ChEMBL
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	7.38	7.38	7.38	ChEMBL
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pKi	7.12	7.74	8.36	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	6.70	6.70	6.70	Guide to Pharmacology
5-HT_1E	5HT1E	Human	5-Hydroxytryptamine	A	pKi	5.40	5.40	5.40	Guide to Pharmacology
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	6.80	7.15	7.50	Guide to Pharmacology
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	6.56	7.26	7.60	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	7.40	7.95	8.50	Guide to Pharmacology
5-HT_2B	5HT2B	Rat	5-Hydroxytryptamine	A	pKi	7.60	7.60	7.60	Guide to Pharmacology
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	7.50	7.65	8.00	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	6.50	7.50	8.50	Guide to Pharmacology
5-HT_2C	5HT2C	Rat	5-Hydroxytryptamine	A	pKi	7.20	7.20	7.20	Guide to Pharmacology
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	7.56	7.88	8.10	ChEMBL
5-HT_5A	5HT5A	Mouse	5-Hydroxytryptamine	A	pKi	5.06	5.06	5.06	ChEMBL
5-HT₆	5HT6R	Rat	5-Hydroxytryptamine	A	pKi	5.60	5.60	5.60	Guide to Pharmacology
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	5.64	5.70	5.76	ChEMBL
5-HT₇	5HT7R	Rat	5-Hydroxytryptamine	A	pKi	6.40	6.50	6.60	Guide to Pharmacology
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pKi	6.52	6.65	6.79	ChEMBL
5-HT₇	5HT7R	Rat	5-Hydroxytryptamine	A	pKi	6.45	6.45	6.45	ChEMBL

Showing 1 to 20 of 20 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

β₁	ADRB1	Human	Adrenoceptors	A	pIC50	5.70	5.70	5.70	ChEMBL
β₂	ADRB2	Dog	Adrenoceptors	A	pIC50	4.75	4.75	4.75	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pEC50	6.54	6.95	8.14	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pEC50	6.54	6.89	7.40	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pEC50	6.77	7.62	8.10	ChEMBL
M₁	ACM1	Rat	Acetylcholine (muscarinic)	A	Potency	4.70	4.75	4.80	ChEMBL

Showing 1 to 6 of 6 entries

m-chlorophenylpiperazine

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank GPCRdb

Compound is not listed as a drug.