GPCRdb

CHEMBL584046

Agent/drug
Bioactivity

CHEMBL584046

SMILES	CN(C)CCn1cc(S(=O)(=O)c2cccc(Cl)c2)c2cccnc21
InChIKey	QFJMKWALUAWNKC-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	0
Rotatable bonds	5
Molecular weight (Da)	363.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	8.64	8.64	8.64	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pIC50	6.88	6.88	6.88	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pIC50	6.32	6.32	6.32	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pEC50	7.82	7.82	7.82	ChEMBL
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pIC50	5.92	5.92	5.92	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL584046

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.