CHEMBL64461


SMILES O=C(c1ccc(OCCCN2CCN(C(=O)[C@H]3CCCN3)CC2)cc1)C1CC1
InChIKey JZOQPCYGADPKSS-HXUWFJFHSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 385.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.52 7.52 7.52 ChEMBL
H2 HRH2 Human Histamine A pKi 4.27 4.27 4.27 ChEMBL
H1 HRH1 Human Histamine A pKi 4.43 4.43 4.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database