GPCRdb

impentamine

Agent/drug
Bioactivity

impentamine

SMILES	NCCCCCc1cnc[nH]1
InChIKey	MZCJWLAXZRFUPI-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	5
Molecular weight (Da)	153.1

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Ligand site mutations	H₃

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pKi	8.30	8.30	8.30	Guide to Pharmacology
H₃	HRH3	Rat	Histamine	A	pKi	8.30	8.30	8.30	Guide to Pharmacology
H₃	HRH3	Guinea pig	Histamine	A	pKd	8.40	8.40	8.40	ChEMBL
H₃	HRH3	Human	Histamine	A	pKi	7.43	8.08	8.30	ChEMBL
H₄	HRH4	Human	Histamine	A	pKi	6.20	6.47	6.60	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pEC50	8.30	8.44	8.63	ChEMBL

Showing 1 to 1 of 1 entry

impentamine

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Ligand site mutations	H₃

Compound is not listed as a drug.